Laryngeal spray salbutamol with nasopharyngeal cannula

Bronchodilator

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Horses with lower respiratory airway inflammations: acute bronchial obstruction SAID, RAD, COPD (chronic obstructive pulmonary diseases), EIPH (exercise induced pulmonary hemorrhage) or any of these diseases can keep on training with the application of Spray Laríngeo Salbutamol by means of its nasopharyngeal cannula.

These sprayings are applied directly in the pharyngeal cavity with a flexible cannula through the nasal passages. The pharynx performs as an expansion chamber for the big drops to deposit thus permitting drops smaller than 3 microns that stay in suspension be carried by the inspiratory flux into the lungs. This spray can also be applied intra-tracheally using a special needle accessory.


Spray Laríngeo Salbutamol (Albuterol), due to its propelling force with fine drops, is the only device that allows the exact application and dosage on the bronchi and bronchioles.

The suspension must be used only locally through the spray. Its nasopharyngeal cannula allows direct application and dosage by spraying the lung region.

Apply 20 minutes before exercise or immediately in acute bronchial obstruction. The effect lasts for 4 to 6 hours.

Easy to use:

Introduce the cannula, forward through the ventral meatus until reaching the zone to be treated; shake well and attach the canister, extend the equine's head, close the nostrils briefly to induce a slightly profound inspiration and press twice. Detach the cannister, re-shake, re-attach and repeat the procedure with the next inspiration.

FORMULA:

Each dose (1 puff) contains 200 mcg of micronized base Salbutamol in pressurized container, with dosing valve and nasopharyngeal cannula and adapter for intra-tracheal application.

Excipients and propellants for 60 doses.

(Discard canister after 60 doses).

THERAPEUTIC USE:

Spray Laríngeo Salbutamol is a selective agonist of beta-2 adrenergic receptors of de bronchial smooth muscle. Salbutamol produces smooth muscle relaxation in the lungs (big bronchi, bronchi and bronchioles), remarkably improving breathing. When applied at therapeutic doses it produces bronchodilation with scarce or no side effects on cardiac beta-1 adrenergic receptors.

Salbutamol inhibits immediate and late bronchoial obstruction and prevents acute bronchial obstruction induced by exercise and exposure to triggering factors (sulfur dioxide, cold air, etc.). Bronchodilation is almost immediate and lasts from 4 to 6 hours.

INDICATIONS:

Especially indicated for equines presenting acute bronchial obstruction: SAID, RAD, COPD (Chronic obstructive Pulmonary disease) EIPH (Exercise Induced Pulmonary Hemorrhage), pulmonary emphysema, bronchoconstriction induced by exercise, acute and chronic bronchitis and in cases of bronchial hyper-reactivity in equines that are hypersensitized to dose allergens triggering acute bronchial obstruction.

DOSAGE & ADMINISTRATION:

Extend the equine's head as far as possible, and with the use a twitch, introduce the cannula trough the ventral meatus of the nasal cavity to the pharynx.

Shake the canister energetically before use and attach the cannula.

Hold the canister upside down with the arrow (label) pointing upwards.

Cover the nostrils of the horse to make it hold its breath for about 15 seconds.

Release the nostrils and when the inspiration starts, press the valve twice (2 puffs) thus delivering 400 micrograms.


Shake again and repeat the operation with the next inspiration, performing 1 or 2 more puffs so as to complete the dose prescribed by the Veterinarian (600 or 800 micrograms). This way, the pharynx and the trachea are used as an expansion chamber and deposit the bigger particles, thus leaving those particles smaller than 3 microns in suspension, diminishing resistance from de upper respiratory airways, carrying the particles deep into the lower respiratory airways by the inspiratory flux. The treatment must be applied 30 minutes before exercise, and the effect last from 4 to 6 hours.

In the case of acute bronchial obstruction, apply immediately.

INTRATRACHEAL ADAPTER (sold separately):

If using the intra-tracheal special needle accessory, introduce a 18/21 gauge x 1'' in any intercartilaginous area of the trachea. The needle must be kept longitudinal to the trachea.
When taking the needle out of the trachea (a septic means) some microorganisms may deposit on the subcutaneous tissues.


This featured accessory is for exclusive use by Veterinarians and is sold separately.

THE FOLLOWING STEPS MUST BE FOLLOWED WHEN USING SPRAY LARINGEO SALBUTAMOL IN ORDER TO MAKE CERTAIN THAT THE CORRECT DOSAGE IS APPLIED. IT IS VERY IMPORTANT THAT THESE STEPS BE TAKEN TO INSURE THAT THE SALBUTAMOL REACHES THE BRONCHIOLES.

1. Spray Laríngeo Salbutamol must always be applied with the canister in inverted position (with arrow on label pointing up) and always held in vertical position (not inclined).
2. Shake Spray Laríngeo Salbutamol thoroughly.
3. Apply twitch to upper lip.
4. Place the head of the horse in the same line as the neck.
5. Connect the cannula to the canister.
6. Introduce half the cannula through one of the nostrils.
7. Cover nostrils to stop breathing for a short period of time in order to induce a slightly profound inspiration.
8. Shake again and introduce the cannula completely.
9. Release nostrils and when breathing begins, press twice (2 puffs). This releases 400 micrograms. (the "puff" does not make any noise and cannot be heard)
10. Extract the cannula halfway and shake again.
11. Reintroduce the cannula completely and apply two more puffs during the next inspiration, thus completing the dosage with a total of 800 micrograms.

The cannula and the adapter for the intra-tracheal needle must be washed through with a green cone needle (21 g) after it is used. Shake the cannula to remove excess water and leave out to dry, then disinfect. The blockage caused by accumulation of medication could cause an incorrect dosage, therefore, it is important to keep the cannula and intra-tracheal adaptor needle clean.